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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

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In fact, it is difficult to define leptin resistance in a universal and quantifiable manner, but understanding of the mechanisms that attenuated leptin action could provide new insights to decipher the myth of leptin resistance and obesity

The BBB here thus play an even more important role as it is necessary to find treatment options that can cross the BBB and reach the brain

In addition, mitochondria also produce a large amount of ROS during normal metabolism and the generation of cellular energy via the electron transport chain, leading to cell and tissue damage [36]